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Pathology Revision Notes

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Quick Reference — All Topics

1. Cellular Adaptation & Apoptosis

💡 Apoptosis = Bax/Bak (pro), Bcl-2 (anti). No inflammation in apoptosis.

2. Anemias & Leukemias (CML, AML)

💡 CML = t(9;22) BCR-ABL. AML = Auer rods. CLL = Smudge cells.

3. Neoplasia Hallmarks & Genes

💡 p53 = Guardian of genome. Rb = Retinoblastoma, Osteosarcoma.

4. Systemic Pathology (Cardio, Resp, Renal)

💡 Minimal change disease = Podocyte effacement, kids. Nephritic = RBC casts.